IGF-1 (Insulin-like Growth Factor 1)

IGF-1 (Insulin-like Growth Factor 1) – is a protein that is produced in the liver in response to stimulation by growth hormone (GH). It is an important factor in the regulation of growth and development, including height growth. IGF-1 is released into the bloodstream and acts as a mediator of the effects of growth hormone on various tissues and organs in the body.

IGF-1 plays a crucial role in the growth and development of bones, muscles, and other tissues during childhood and adolescence. It stimulates cell proliferation, differentiation, and tissue growth, particularly in the long bones of the body, which are responsible for height growth. IGF-1 promotes bone growth by stimulating the production of new bone cells (osteoblasts) and enhancing the absorption of calcium and other minerals necessary for bone mineralization.

During periods of rapid growth, such as puberty, the levels of IGF-1 in the body are typically higher, which contributes to the growth and elongation of long bones, resulting in increased height. However, the production of IGF-1 is tightly regulated by various factors, including growth hormone levels, genetics, nutrition, and overall health status.